"Private Practice" was picked up for 13 episodes for its sixth season in the fall, and Walsh is committed to only those 13 episodes, Deadline.com reports. An ABC rep did not immediately respond to TheWrap's request for comment, while a rep for Walsh declined to comment.
News of Walsh's upcoming departure comes on the heels of co-star Tim Daly's announcement earlier this week that his contract had not been renewed for the show's sixth season.
"Private Practice" was considered to be on the bubble at the end of season five, so with two major cast members out and only a 13-episode commitment from the network, the show's sixth season could be its last.
Walsh's next project is playing the mom, with Dylan McDermott as the dad, in the movie adaptation of "The Perks of Being a Wallflower." The trailer for the September movie debuts during the pre-show of the MTV Movie Awards on Sunday.
Meanwhile, Walsh commented on Twitter this week about Daly's departure, but of questions surrounding her own future with "Private Practice," she tweeted this: "Tw'eeps, I'd like you to address all of your questions to this guy," with a link to a photo of ... her cat.