New Girl will now air on E4 rather than Channel 4 because the broadcaster believes the show has a stronger appeal with the sister channel's younger audience, reports Broadcast.
New Girl still has 13 episodes of its 24-episode run to air in the UK.
A Channel 4 rep said: "We're constantly looking at what's best for our content across the portfolio of channels and while we were very happy with New Girl's performance on C4, we saw that the profile of New Girl was skewing significantly younger than the C4 slot average and was more in line with the E4 target demographic.
"E4 is the ideal UK home for Jess and the guys and we're very excited to see them move there in June."
New Girl has been picked up for a second series by Fox in the US and has been a ratings hit.
The comedy - starring Deschanel, Jack Johnson, Max Greenfield and Lamorne Morris - picked up decent figures in the 8.30pm slot on Fridays on Channel 4, but proved even more successful on the broadcaster's catch-up services, regularly topping their monthly charts.
