The procedural, led by Rachael Carpani, debuted to 1.8 million viewers in July.
Lifetime has decided not to order a second season of Against the Wall.
Cast member Brandon Quinn tweeted the news late Friday evening, writing, "I'd like to thank @lifetimetv, the #AgainsttheWall writers and the Amazing fans of Against The Wall but unfortunately we've been canceled :(."
The writers addressed the news shortly thereafter, writing on their Twitter account, "guessing many of you saw @BrandonJQuinn's tweet -- just found out we won't be coming back for a second season."
Starring Rachael Carpani as a Chicago cop who joins the internal affairs division, the procedural debuted in July to underwhelming numbers, drawing 1.8 million total viewers to its premiere episode following Drop Dead Diva.
THR's television critic Tim Goodman gave a positive review of the hourlong series: "Breakout star Rachael Carpani and ambitious creators could vault this procedural above the pack."
The Universal Cable Prods. series was created by Annie Brummer and co-stars Quinn, Andrew Walker, Marisa Ramirez, Kathy Baker, Treat Williams and Chris Johnson.
The decision comes at a time when Lifetime is investing in remakes with core audiences like Steel Magnolias and The Blue Lagoon, with high-profile names attached. The female-skewing cable net has also given pilot orders to Modern Love by Jenny Bicks and American Housewife with Melanie Griffith, and has picked up The Client List with Jennifer Love Hewitt to series.
